The DETOX-Responsible Innovation Project
1 January 2016 - 1 January 2021
PI/s in Exeter: Professor Susan Molyneux-Hodgson
Research partners: Academic research partners: Universities of York (PI: Prof. Gavin H. Thomas); Sheffield, Nottingham and Cambridge Industrial partnerships: Lucite International, Green Biologics, Ingenza, and CPI.
About the research
Project DETOX was launched in 2016 through the award of a 5-year Translation Grant through the Industrial Biotechnology Catalyst (Innovate UK, BBSRC, EPSRC). It is led from the Department of Biology at the University of York by Dr. Gavin H. Thomas with collaborators at the Universities of Nottingham, Sheffield, Exeter and Cambridge. Working with industrial partners Lucite, Green Biologics, Ingenza and CPI, the team aim to understand the physiological changes that microbes use to enable survival when exposed to bio-manufacturing chemicals that are toxic to them. DETOX solutions will then provide engineered chassis strains for its key partners for use in bioproduction to yield higher final titres of product – a problem that currently limits the financial viability of some processes.